Severe Acute Interstitial Nephritis: Response to Therapy With Antithymocyte Globulin
نویسندگان
چکیده
Tiffany Shao, Jordan Weinstein, Serge Jothy and Marc Goldstein Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Nephrology, Department of Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada; and Department of Laboratory Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada
منابع مشابه
Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia
For treatment of severe aplastic anemia, immunosuppressive therapy with horse antithymocyte globulin results in superior response and survival compared with rabbit antithymocyte globulin. This relative benefit may be different in the setting of transplantation as rabbit antithymocyte globulin results in more profound immunosuppression. We analyzed 833 severe aplastic anemia transplants between ...
متن کاملLong-term outcome after immunosuppressive therapy with horse or rabbit antithymocyte globulin and cyclosporine for severe aplastic anemia in children.
Some prospective studies showed that rabbit antithymocyte globulin was inferior to horse antithymocyte globulin as first-line therapy for patients with severe aplastic anemia. We retrospectively analyzed the clinical outcome of 455 children with severe aplastic anemia who received horse antithymocyte globulin (n=297) or rabbit antithymocyte globulin (n=158) combined with cyclosporine as first-l...
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Concurrence of interstitial nephritis and uveitis named tubulointestitioal nephritis and uveitis syndrome (TINU) are unusual and uncommon presentations of interstitial nephritis. This syndrome is considered after ruling out other differential diagnoses. A-38-year old man presented with acute renal failure and uveitis. The histologic findings of renal biopsy showed acute tubulointestitioal nephr...
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Introduction: Prevalence of infective endocarditic induced renal failure is 1-3% and is one of the causes of deterioration of patient or cessation of antibiotic therapy and also delay in treatment duration and medical response. Case Report: Our patient is a 48 year old man with infective endocarditis who had been under treatment by antibiotics (cefteriaxone, gentamycin and vencomycin) and exp...
متن کاملOutcome of children with severe acquired aplastic anemia treated with rabbit antithymocyte globulin and cyclosporine A.
OBJECTIVE To evaluate the outcome of children with severe acquired aplastic anemia treated with rabbit antithymocyte globulin and cyclosporine as first-line treatment at this institution. METHODS Retrospective analysis of 26 pediatric patients with aplastic anemia, treated between 1996 and 2011 with rabbit antithymocyte globulin plus cyclosporine. RESULTS The overall response rate at six mo...
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